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Solubility
Enhancement
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It takes more than
logS and logP
to predict solubility. |
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Adoption
of the BCS system by pharmaceutical companies has led to logS and logP
being used as a guide to formulation. Unfortunately, this greatly
oversimplifies the challenge and, in many cases, results in repeated
early phase work.
A Patheon analysis of drugs brought to market over the past three
decades shows that approved drugs do not follow clear trends when only
these two measures are considered. Download our report to learn how a
broader review of first-order properties improves the chances of getting
solubility right the first time. |
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| Download: How Broadening the Analysis of Compound Factors Allows for Predictive Solubility Solutions |
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