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Case Study on Quantitation and Characterization of

Polysorbate-80 in Drug Formulations

Polysorbate-80 (PS-80) is a surfactant commonly used as an excipient to improve API stability. However, degradation of PS-80 can lead to decreased drug potency or stability, and there is inconsistency in the quality and composition of PS-80 provided by different vendors.


Download this case study to learn the following:

  • Challenges associated with the heterogeneous nature of PS-80 when used as an excipient
  • Strategies to quantitate and characterize PS-80
  • How this combined approach can measure PS-80 stability and homogeneity
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